Canon imageRUNNER ADVANCE 4500 III Series Review

Good: Enhanced security features, 10.1" color flat panel control panel, Staple-free Stapling and Staple On Demand for finishers
Bad: Not intended for very small offices.
Bottom Line: Third-generation imageRUNNER ADVANCE black-and-white MFPs with a strong focus on security.
Intended Users:
iR ADVANCE 4500 III Series
All sizes
Speed Black:
Speed Color:
25 ppm-51 ppm
Not applicable
Canon Dual Custom Processor
3 GB

Product Overview

Canon has refreshed its third-generation imageRUNNER ADVANCE series with the the new third edition models. The new edition includes upgraded security features, such as the integration with the customers’ exiting Security Information Event Management (SIEM) solution. Integration to SIEM allows IT professionals to include the Canon imageRUNNER ADVANCE device into their company’s existing comprehensive security monitoring. In other words, they’ll have insights into potential threats to their infrastructure, including their print fleet, without having to manually import data from the printer into the SIEM solution. SIEM integration is now also available on all third-generation imageRUNNER ADVANCE models through Canon’s Unified Firmware Platform, which frequently provides new features and functionalities through firmware updates.

Additional new security features include the Verify System at Startup process, only available on third edition models, that uses a Root of Trust to help protect the device from unauthorized modifications and an automatic security certificate update that helps reduce the burden on IT staff.

The imageRUNNER ADVANCE 4500 III Series is a series of black-and-white MFPs targeted to all organizations from smaller businesses to enterprise-level operations. There are four devices, and they all offer standard printing, copying and scanning with optional faxing. With the exception of speed and document feeder, they all share identical specifications.

The four devices are:

  • The imageRUNNER ADVANCE 4525i III copies and prints at 25ppm and has a first-copy-time of 5.2 seconds,
  • The imageRUNNER ADVANCE 4535i III copies and prints at 35ppm and has a first-copy-time of 3.8 seconds,
  • The imageRUNNER ADVANCE 4545i III copies and prints at 45ppm and also has a first-copy-time of 3.8 seconds, and
  • The imageRUNNER ADVANCE 4551i III copies and prints at 51ppm and has a first-copy-time of 3.7 seconds.

All four models include the Canon Dual Custom Processor, 3 GB of memory and a 250 GB hard drive that can be expanded to 1 TB. There is also a 10.1″ color control panel with a flat touchscreen that works like a smartphone.  The control panel uses a feature called My ADVANCE that allows each user to customize specific features (i.e. a personal address book) based on their specific workflows.

Printing language, such as PCL, PostScript and Canon’s proprietary UFR II, is supported. USB, Ethernet and Wi-Fi connectivity are also standard. The devices support mobile printing and scanning with Canon’s PRINT Business app.

More details on the devices’ features are in our Features section below.

Canon has consistently improved upon its MFPs with better upgrades over the years and the imageRUNNER ADVANCE 4500 III Series is no exception. They provide strong features and scalable options for an office that expects to have medium or high-volume printing needs.


Paper handling: All devices include standard dual 550-sheet paper trays and a 80-sheet bypass. Canon offers additional paper trays as options, such as two more 550-sheet trays, a 2,700-sheet paper deck unit and a high-capacity 2,450-sheet feeding unit. The maximum capacity is 6,330 sheets.

Automatic duplexing is supported. The 4545i III and 4551i III includes a standard 150-sheet single-pass duplexing document feeder. It has a scanning speed of up to 80 ppm simplex (160 ipm duplex). The 4525i III and 4535i III, on the other hand, has a standard 100-sheet automatic document feeder (the single-pass duplexing feeder is only optional).

Standard output capacity is 250 sheets. There are a few finishing options. First, there is an inner finisher with a two-tray 545-sheet capacity and 50-sheet multiposition stapling. There is an optional 2/3-hole punch with this finisher. Second, there is an external stapling finisher with a two-tray 3,250-sheet capacity and 50-sheet multiposition stapling. It also includes an optional 2/3-hole punch kit. And finally, users can add a booklet finisher that includes two trays with a 3,250-sheet capacity, 50-sheet multiposition stapling and 20-sheet booklet making capability.

We want to note that all three finishers supports Canon’s Staple-free Stapling and Staple On Demand features. Staple-free Stapling allows the user to stack and staple finished documents (up to five pages) with the use of a pressure bind instead of staples. Staple On Demand lets users re-staple originals after any copying or scanning is done or staple printed paper without having to select any stapling settings. Both features were designed to help improve efficiency and productivity in producing finished documents.

Scanning and faxing: The color scanning function allows for sending scans to multiple destinations, such as email, SMB and mailbox. It supports file formats, such as TIFF, JPEG and compact and searchable PDF. Optional formats include encrypted PDF and PDF with digital signature. LDAP is also supported.

The devices include document storage functionality with a maximum of 100 user in-boxes that includes a capacity of 30,000 pages stored. The Advanced Box mailbox and storage system that allows users to store work in an expanded number of shared boxes on hard drive. It also allows users anywhere on the network to store files created on their PCs, and is accessible, subject to authentication.

The faxing funtion uses a 33.6 kbps modem with JBIG compression and up to 30,000 pages in fax memory.

Security: The Canon imageRUNNER ADVANCE 4500 III Series include many security features, both standard and optional. Some of the standard features include user authentication, device and function-level log-in, hard disk drive erase, IP/Mac address filtering, secure watermark and secure print, to name several. Optional security features include hard disk drive mirroring, hard disk drive removal and document scan locking.

  • Automatic Document Feeder?
  • Duplexing?
  • Ethernet Connectivity?
  • Wireless Connectivity?
  • Mobile Printing/Scanning?
  • Finishers?


Although Canon touts these devices as targeted for SMBs, they may be too expensive or too fast for very small offices. Those offices can check out our reviews on other Canon devices or other MFPs.


Canon is the number-one copier company in the U.S. if measured by the total number of units sold.

The company has an impressive line of multifunctional devices, and it’s one of the leaders in this market. Most of Canon’s multifunction printer (MFP) line carries the imageRUNNER brand name.

Over the years, Canon’s print controller strategy has involved partnering with EFI, the third-party controller company that dominates the color market. The company also relies on controllers developed by Canon itself. The controllers, which feature Canon’s IP architecture (the “IP” stands for “Image Platform”), can be found on all imageRUNNER models.

Canon’s MEAP architecture (Multifunctional Embedded Application Program) has been a significant addition to Canon’s controller strategy. It’s featured on most of its mid-to-high-volume models. The MEAP platform features an open architecture for providing custom software applications, some for private use and others sold on the open market as add-on products from third parties.

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